Search results for "Dane Particle"
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Demonstration and partial characterization of an intermediate HBcAG (Dane particle) population.
1981
Abstract Hepatitis-B core antigen (HBcAg) was released from Dane particles previously separated from anti-HBc by repeated pelleting through sucrose gradients separated into three HBcAg populations when analysed by cesium chloride density gradient centrifugation. Heavy HBcAg particles banded at a density of 1.355 gm/ml, intermediate HBcAg particles at a density of 1.33 gm/ml, and light mediate HBcAg particles at a density of 1.30 gm/ml. Like heavy HBcAg particles, intermediate HBcAg particles contained DNA polymerase activity, but the ratio of HBcAg to DNA polymerase activity was significantly different in both populations. Intermediate HBcAg particles could not be separated from heavy HBcAg…
Viral Hepatitis — An Update
1983
In 1973, Feinstone and co-workers [52] were the first to report the visualization of virus-like particles by immune electron microscopy in acute phase stool specimens of human volunteers who developed hepatitis following inoculation with MS-1 strain of hepatitis A virus [18]. Soon thereafter morphologically identical particles were recovered from the stool of individuals acquiring hepatitis during natural outbreaks of the disease [39, 64].